HILIC相关论文
99m Technetium(Tc)-based complexes are widely used as contrast agents for medical diagnostics....
Development and validation of an HILIC-MS/MS method by one-step precipitation for chloroquine in min
Background: Quantification of polar compounds such as chloroquine by revered-phase liquid chromatography is a challenge ......
Metabolomic identification of potential biomarkers for acute graft rejection of renal transplantatio
Acute graft rejection is a major post-transplant complications of renal transplantation, the success of renal transplant......
目的：开发一种集灵敏度、样品制备通量、操作简单性于一体的游离N-糖制备方法,用于HILIC分析,并评估其性能。方法：基于合理设计,合成......
Evaluation of RPLC,HILIC and SFC for the Chromatographic Resolution of Some Relatively Polar Constit
Traditional Chinese Medicine (TCM) represents an active, multi-disciplinary research area that often starts with isolati......
Preparation of Bis-amino stationary phase and its application in hydrophilic interaction liquid chro
Hydrophilic interaction liquid chromatography (HILIC) is an alternative method to reversed-phase liquid chromatography (......
Grafting of silica with a hydrophilic triol acrylamide polymer via surface-initiated “grafting from”
The increasing demand for the analysis of polar compounds in biological and environmental samples promotes the developme......
Hydrophilic interaction liquid chromatography (HILIC) plays an important role in the separation of polar compounds.The d......
Investigations on polyamine chromatographic behavior in hydrophilic interaction liquid chromatograph
Hydrophilic interaction liquid chromatography (HILIC) proposed by Alpert in 1990 is now an alternative method for polar ......
Novel separation materials for HPLC and applications in the separation of traditional chinese medici
Developing novel HPLC separation materials is one of the most important approaches to resolve the emerging separation pr......
Investigation of Selectivity on Sulfobetaine and Phosphorylcholine Bonded Zwitterionic HILIC Station
Hydrophilic interaction liquid chromatography (HILIC) has developed rapidly in the past decade because of its excellent ......
Glycomic analysis of Recombinant Erythropoietin Biotherapeutics by Capillary Electrophoresis and Ult
Glycosylation impact the pharmacokinetics,pharmacodynamics and/or efficacy of glycoprotein therapeutics1.Erythropoietin(......
N-glycosylation is one of the most common and complex post-translational modification of proteins, which plays an import......
Evaluation of newly developed 3 micron HILIC columns for separation of hydrophilic compounds includi
Three micron hydrophilic interaction liquid chromatography (HILIC) columns, TSKgel Amide-80 3μm were developed for use ......
Better Understanding of HILIC Impact of changed pH and pKa values due to high Acetonitrile Concentra
Since recent years HILIC (aqueous normal-phase,ANP) gained more interest[1,2].Reasons for this interest are based on......
Comprehensive 2D Liquid Chromatography(LC×LC) Analysis of Nonylphenol Polyethoxylates by Using HILIC
Analysis of surfactants is a common requirement of analytical and technical laboratories.Surfactants based on polyet......
Isolation and Structural Analysis of N-Linked Glycans by Using Two-dimensional Chromatography,Mass S
For in-depth understanding the biofunctions of glycans attached to proteins,it is the first priority to acquire thei......
亲水作用液相层析（HILIC）是一种分离全细胞溶解产物的新型层析技术。在蛋白质组学中，利用HILIC可以降低全细胞溶解产物分离的复杂性，便......
目的：建立UPLC法Hilic模式下测定促胰岛素分泌肽类似物（Ex4c）有关物质的方法。方法：色谱柱为Waters ACQUITY UPLC BEH Amide C18（150 mm......
目的建立LC-MS/MS测定硫酸氢氯吡格雷中的痕量四乙基溴化铵。方法采用Waters Atantis HILIC silica色谱柱(2.1 mm×100 mm,5μm),......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
建立亲水色谱-蒸发光散射检测器-电喷雾-四级杆-飞行时间串联质谱(HILIC-ELSD-ESI-Q-TOF/MS)技术用于工业低聚麦芽糖中化学成分的......
目的：建立亲水作用色谱-蒸发光散射检测器联用测定盐酸多巴酚丁胺注射液中亚硫酸氢钠和依地酸二钠含量的方法。方法：采用ZIC—HILIC......
建立使亲水色谱柱同时测定硝酸盐和亚硝酸盐的高效液相色谱方法。样品匀浆后超声提取,高速离心处理,采用亲水色谱柱分离,乙酸铵和......
目的：建立亲水作用色谱测定盐酸多巴酚丁胺注射液中盐酸半胱氨酸含量的方法。方法：采用默克ZIC-HILIC柱（150 mm×4.6 mm,5μm）；乙腈......
试验采用氨基柱（150 mm×4.6 mm,5μm粒径,10nm孔径）,流动相A：CH3CN;流动相B：5 mM乙酸铵水溶液;梯度：0～5 min（5%～30%B）,50～60 min（30%B）;检......
建立了同时检测预混合饲料中7种抗病毒药物含量的分散固相萃取（Qu CHERS）结合亲水作用色谱（HILIC）-串联质谱检测方法,包括了金刚烷胺、......
目的建立木香顺气丸中辛弗林的含量测定方法。方法采用TSK Amide80色谱柱（4.6 mm×150m,5μm）,以乙酸氨溶液13mM（pH6.7）-乙腈（v/v 1......
采用亲水作用高效液相色谱法（HILIC）测定长春瑞滨含量。对方法的精密度、最低检出限度、重复性、稳定性进行了系统研究。本方法能够......
通讯因素分析(CFA ) 被采用学习 14 个 HPLC 系统的选择。测试 LC 系统作为反向阶段被分类(RP ) ，离子交换(IE ) 和吸水的相互作用......
基于亲水相互作用色谱（HILIC）技术，建立了可用于乳制品中尿素测定的液相色谱方法，其中固定相为Polar-Silica色谱柱，流动相为4mmol／L磷酸......
研究目的:低氧是实体肿瘤中普遍存在的病理现象,在低氧微环境下舌癌细胞迁移和侵袭能力显著增强。近年研究发现长链非编码RNA HILI......
为了完善植物生长延缓剂残留检测技术,建立了快速测定蔬菜中3种强极性植物生长延缓剂（矮壮素、缩节胺和丁酰肼）的Qu ECh ERS-HILIC-M......
目的:为EPO分析建立两种简易的基于LC的互补方法,分别用于获取N-糖基化和0-糖基化的相关信息。方法:借助采用新型糖基标记试剂Rapi......
草甘膦,别名达农,化学名N-（膦酸甲基）甘氨酸,属高效、低毒、广谱灭生性除草剂[1],被广泛用于农、林等行业。绿色和平组织报告显示,草......
本研究建立使HILIC柱同时测定蔬菜中硝酸盐和亚硝酸盐的高效液相色谱方法。样品匀浆超声提取,高速离心处理后,使用HILIC色谱柱,乙......
糖组学是研究糖链结构与功能之间相互关系的一门科学,主要研究对象为各种生物体糖蛋白整套不同结构的糖链。但是,糖链结构非常复杂......
[目的]建立亲水作用色谱-紫外检测器测定氰胺基甲酸甲酯中残留单氰胺和双氰胺的分析方法,为合成工艺优化和产品质量分析提供支撑。......
随着抗体制备技术、荧光示踪标记技术、色谱质谱技术的不断发展,小分子化合物的新的检测模式和检测方法也不断涌现。氨基糖普类(AG......
基于素水相互作用色谱（HILIC）技术,建立了可用于茎直黄芪中苦马豆素测定方法.样品用甲醇提取,挥干后用0.05M盐酸溶解,氯仿和水饱和正......
